WELCOME DR. SHAPIRO: I would like to call our meeting to order. We have a long and a full agenda today so I think we better get under way. For those of you that were not with us yesterday, I want to announce once again that we have to my right, Eric Meslin, who is now our director. I want to welcome him. We are very fortunate to have been able to attract him. As many of you know, he has had a series of interesting and distinguished posts. We have, as someone mentioned yesterday, just pirated him from ELSI and we are very pleased to do so. I welcome him. I will take the opportunity, also, once again to thank Bill Raub, who has served in an acting capacity for us for a good part of last year. Now, we will begin this morning by discussing the ongoing work of the Human Genetics Subcommittee which met yesterday and had what I thought was a very interesting discussion and we will hear more about that in just a few moments. I will turn to Tom. That will be our first major item on our agenda. Most of the afternoon we will be doing work with the Human Subjects Subcommittee. And we have a few very important guests here today as well. There has been a change in the agenda, just a rearrangement of items. I think everyone has got a copy of the current agenda in front of them. If you would just take the issue "Future Commission Research Activities" and put that as the first item after lunch that had been, if I remember correctly, the last item of the day. I have put that first after lunch because unfortunately late in the afternoon I will have to leave perhaps before we are able to adjourn and I wanted to make sure as many of us as possible were here for that discussion. If I do have to leave while some of the discussion is going on I apologize to my fellow commission members and to any guests who may be participating in the discussion. So, we have quite a few items and I think we just ought to get going and let me turn first, then, to Tom and the report of the Genetics Subcommittee. Tom? If I could just make one more comment. Someone said yesterday the sound system here is the rock star variety, that is you have to talk very close to the microphone in order for it to really work and please jump up and wave your hand if we are not -- to our technician and helper here if we are not doing this properly. So thank you very much. Tom?